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Home - Products - Immunology/Inflammation - Lipoxygenase - RWJ 63556

RWJ 63556

CAS No. 190967-35-2

RWJ 63556( RWJ-63556 )

Catalog No. M26425 CAS No. 190967-35-2

RWJ 63556 is an orally active inhibitor of COX-2 selective/5-lipoxygenase, shows anti-inflammatory activities.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    RWJ 63556
  • Note
    Research use only, not for human use.
  • Brief Description
    RWJ 63556 is an orally active inhibitor of COX-2 selective/5-lipoxygenase, shows anti-inflammatory activities.
  • Description
    RWJ 63556 is an orally active inhibitor of COX-2 selective/5-lipoxygenase, shows anti-inflammatory activities.(In Vitro):RWJ 63556 is a potent leukocyte influx inhibitor over a period of 24 hr and maintains its in vitro profile on eicosanoids.(In Vivo):RWJ 63556 (1?mg/kg, i.v.) significantly inhibits the development of SP-induced oedema.
  • In Vitro
    RWJ 63556 is a potent inhibitor of leukocyte influx over a period of 24 hr and maintains its in vitro profile on eicosanoids.
  • In Vivo
    RWJ 63556 (1?mg/kg, i.v.) significantly inhibits the development of SP-induced oedema.
  • Synonyms
    RWJ-63556
  • Pathway
    Immunology/Inflammation
  • Target
    Lipoxygenase
  • Recptor
    VHL
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    190967-35-2
  • Formula Weight
    287.32
  • Molecular Formula
    C11H10FNO3S2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (348.03 mM)
  • SMILES
    CS(=O)(=O)Nc1ccc(Oc2ccc(F)cc2)s1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Pillow TH, et al. Antibody Conjugation of a Chimeric BET Degrader Enables in vivo Activity. ChemMedChem. 2019 Oct 31.
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